01 - Whisk buttermilk with salt, garlic powder, onion powder, cayenne pepper, and black pepper in a large bowl until fully combined. Submerge chicken pieces in marinade, ensuring complete coverage. Cover bowl and refrigerate for minimum 2 hours, ideally overnight for maximum flavor penetration.
02 - Combine flour, paprika, salt, black pepper, cayenne pepper, and baking powder in a separate bowl. Whisk thoroughly to distribute spices evenly throughout the flour mixture.
03 - Remove chicken from marinade, allowing excess liquid to drip off. Dredge each piece in flour mixture, pressing firmly to adhere thick, even coating. Place coated chicken on wire rack and rest for 10 minutes to set crust.
04 - Pour vegetable oil into deep fryer or heavy-bottomed pot until depth reaches 3-4 inches. Heat oil to 350°F, maintaining consistent temperature throughout frying process.
05 - Carefully lower chicken pieces into hot oil in small batches, avoiding overcrowding. Fry for 12-15 minutes, turning occasionally for even browning. Cook until golden brown, crispy, and internal temperature reaches 165°F.
06 - Transfer fried chicken to wire rack or paper towels to drain excess oil. Let rest for 5 minutes before serving to allow juices to redistribute and coating to set.